Margaret was the daughter of Andrew and Sarah Oakley Graham.
Margaret never married.
Margaret lived in Tarrytown until age 67, when a cousin in Ohio died leaving a little girl and two boys. Margaret moved to Zanesville to care for the children. Margaret spent the last nine years of her life raising the children. She died in Zanesville, but requested in her will to be buried in Tarrytown in her father's lot. Margaret was interred at Tarrytown September 6, 1890. She left her entire estate to the children she raised.