She was the wife of Charles, Count of Artois, the future King Charles X of France. Born in Turin, the capital of the Kingdom of Sardinia on 31 January 1756, she was the child of Prince Victor Amandeus of Savoy and his wife the Spanish Infanta Maria Antonietta of Spain. At the time of her birth her paternal grandfather, Charles Emmanuel III of Sardinia, was the King of Sardinia.
She fled France with her husband shortly after the storming of the Bastille (14 July 1789), which marked the beginning of the French Revolution. Some time after, she took refuge in her homeland of Savoy. She died in exile at Graz (Austria) in 1805. Because she died before her husband became king of France, she remained Countess of Artois. She was buried in the Imperial Mausoleum next to Graz cathedral.