She was the daughter of Sir James Leveson of Lilleshall 1487-1545 and his wife Marjory née Offley 1504-1563; sister of Joyce (Gray) and Joan (Fowke); wife of Thomas Creswell and Sir Walter Aston, of Tixall (m.1545); mother of Richard Aston, Sir Edward Aston, of Tixall & Wanlip, Sherriff of Staffordshire; William Aston of Milwich; Catherine Cope; Margery Astley ; Elizabeth (Feilding); Eleanor (Bouldinge); Robert Aston; Mary (Colyer) and Jane (Crompton).